Bright new ideas from Seedcamp

The Guardian brought SeedCamp to my attention the other day, which is like a European KickStarter for entrepreneurs. Lord Sir Alan Sugar would be proud.

The idea is that small startup companies with big ideas can pitch to SeedCamp and get the funding they need to develop or launch their product or service. Or, In SeedCamp?s own words, ?Seedcamp is an early-stage micro seed investment fund and mentoring programme? For the winning companies of any event where we choose to make an investment, Seedcamp?s standard investment is: ?50,000 for 8-10% per cent of the company.?

What caught my eye the most were some of the Guardian?s top 20 picks, which look genuinely fun, useful or some combination thereof. Here are my picks of their picks:

Crowd is in private beta, but is a photo sharing service where users can share images in real-time, allowing people to experience other locations via geo-tagged image taken there.

EnergyBob is just a placeholder URL for the company that aims to make energy metering smarter. The EnergyBob server ?talks to Google's Latitude's API to determine when you're on your way home, and when the heating needs to come on? for example. The appliance is set to cost ?99 for installation and ?9 a month thereafter.

CityMapper is a service that connects the various and many ways to travel around London into one map-driven interface. CityMapper integrates everything from the Tube and buses to the Boris bikes and just walking into one application; it also tells you how much you?ll pay for your journey, or how many calories you?ll burn off. You can use the service now.

Myows stands for ?My Original Works? and is a way to share and distribute your creative work while maintaining control over it. Users store their copyrighted material (which can be images, video, music, artwork or whatever) with Myows, which allows the copyright holder to prove ownership, manage their rights and chase copyright infringements. ?[i] Myows is already storing 18,000 registered works and has solved 72 infringement cases.[i]?

opensignalmaps is a simple idea: overlay the strength of mobile reception on a map. You can select your operator and what level of network you?re looking for (ie, just 3G reception). You can use the service now, and it might come in handy for holidays in remote locations.

Travelstormer might come in handy if you?re arranging a trip with friends, as it helps organise a bunch of people?s travel needs. Once you?ve ?brainstormed? the best plan, you crowdsource travel tips from other Travelstormer users before finalising your plans.

There are more interesting ideas in the Guardian's SeedCamp story and on the SeedCamp site itself.

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Political Memo: A Confident Perry Lingers to Make Friends at the Fair

?Do we have any Aggies in the crowd?? asked Mr. Perry, summoning a voice from his days back on the yell squad at Texas A&M as he looked over a swarm of people who gathered to see his debut here as a Republican presidential candidate. ?We?ve got to have some Aggies in the crowd!?

With that, a cheer rose up and the audience burst into applause. The heckler, similar to one who irritated Mitt Romney and Michele Bachmann at the same spot a few days earlier, was swiftly silenced. As a satisfying smile stretched across his face, he quickly resumed telling voters why he believes he should be the next president.

?I get a little bit passionate,? Mr. Perry said. ?I think you want a president who is passionate about America ? that?s in love with America.?

The introduction of Mr. Perry as an aspiring presidential candidate unfolded in bite-size pieces, with fresh details emerging as he sauntered across the fairgrounds on the third day of his announcement tour. The path had already been well worn by his Republican rivals who camped out in the state last week, but he breezed in like a long-lost visitor, so confident that he blew kisses into a camera when asked about Mr. Romney. ?Give him my love,? Mr. Perry said.

The addition of Mr. Perry to the presidential campaign has changed the landscape of the Republican field ? particularly for Mr. Romney and Mrs. Bachmann ? while injecting a shot of vigor into the contest. Whether making up for lost time or feeling an itch to engage while he had a ready audience, Mr. Perry held a rolling conversation with reporters, interrupted again and again by people rushing over to thank him for joining the race. It continued at an evening stop in Cedar Rapids, when asked if Mr. Obama loved America, he said, ?You?d have to ask him.? He also said Federal Reserve Chairman Ben Bernanke would get ?ugly? treatment in Texas for his policies.

Asked about comparisons to George W. Bush, he said: ?I?m Rick Perry. He?s George Bush. Our records are quite different.? He added, ?I went to Texas A&M; he went to Yale. George Bush is not my opponent.?

Asked about Sarah Palin, he said: ?Sarah is a dear friend. She?ll make the right decision.?

But it was the questions about Mr. Romney that seemed to most engage Mr. Perry.

?Take a look at his record when he was governor. Take a look at my record,? Mr. Perry said. A few minutes later, he added: ?I wasn?t on Wall Street. I wasn?t working in Bain Capital,? forging directly at the critique that Mr. Romney has made against him ? that his credentials are limited to government service, not deep experience in the private sector.

(At nearly the same time in New Hampshire on Monday, Mr. Romney said it was critical to have experience from the ?real economy,? but he refrained from direct criticism of Mr. Perry. He added, ?I?ve learned how the economy works, and I believe that skill is what the nation is looking for.?)

The long-distance exchange, experience in the public sector versus the private sector, highlights a central argument that will be debated until Republicans choose a nominee next year to challenge President Obama. The bumper sticker message of Mr. Perry?s candidacy, ?Getting America Working Again,? is painted on his campaign bus, which on Wednesday will come within a few miles of Mr. Obama?s own bus tour.

?This president has been an abject failure when it comes to the economy,? Mr. Perry said.

For his part, Mr. Perry seemed pleased to take as many questions on the subject that came his way. He paused for a moment, as he reached a patch of shade on a warm afternoon, and told how he would lower the nation?s unemployment rate.

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Political Memo: A Confident Perry Lingers to Make Friends at the Fair

?Do we have any Aggies in the crowd?? asked Mr. Perry, summoning a voice from his days back on the yell squad at Texas A&M as he looked over a swarm of people who gathered to see his debut here as a Republican presidential candidate. ?We?ve got to have some Aggies in the crowd!?

With that, a cheer rose up and the audience burst into applause. The heckler, similar to one who irritated Mitt Romney and Michele Bachmann at the same spot a few days earlier, was swiftly silenced. As a satisfying smile stretched across his face, he quickly resumed telling voters why he believes he should be the next president.

?I get a little bit passionate,? Mr. Perry said. ?I think you want a president who is passionate about America ? that?s in love with America.?

The introduction of Mr. Perry as an aspiring presidential candidate unfolded in bite-size pieces, with fresh details emerging as he sauntered across the fairgrounds on the third day of his announcement tour. The path had already been well worn by his Republican rivals who camped out in the state last week, but he breezed in like a long-lost visitor, so confident that he blew kisses into a camera when asked about Mr. Romney. ?Give him my love,? Mr. Perry said.

The addition of Mr. Perry to the presidential campaign has changed the landscape of the Republican field ? particularly for Mr. Romney and Mrs. Bachmann ? while injecting a shot of vigor into the contest. Whether making up for lost time or feeling an itch to engage while he had a ready audience, Mr. Perry held a rolling conversation with reporters, interrupted again and again by people rushing over to thank him for joining the race. It continued at an evening stop in Cedar Rapids, when asked if Mr. Obama loved America, he said, ?You?d have to ask him.? He also said Federal Reserve Chairman Ben Bernanke would get ?ugly? treatment in Texas for his policies.

Asked about comparisons to George W. Bush, he said: ?I?m Rick Perry. He?s George Bush. Our records are quite different.? He added, ?I went to Texas A&M; he went to Yale. George Bush is not my opponent.?

Asked about Sarah Palin, he said: ?Sarah is a dear friend. She?ll make the right decision.?

But it was the questions about Mr. Romney that seemed to most engage Mr. Perry.

?Take a look at his record when he was governor. Take a look at my record,? Mr. Perry said. A few minutes later, he added: ?I wasn?t on Wall Street. I wasn?t working in Bain Capital,? forging directly at the critique that Mr. Romney has made against him ? that his credentials are limited to government service, not deep experience in the private sector.

(At nearly the same time in New Hampshire on Monday, Mr. Romney said it was critical to have experience from the ?real economy,? but he refrained from direct criticism of Mr. Perry. He added, ?I?ve learned how the economy works, and I believe that skill is what the nation is looking for.?)

The long-distance exchange, experience in the public sector versus the private sector, highlights a central argument that will be debated until Republicans choose a nominee next year to challenge President Obama. The bumper sticker message of Mr. Perry?s candidacy, ?Getting America Working Again,? is painted on his campaign bus, which on Wednesday will come within a few miles of Mr. Obama?s own bus tour.

?This president has been an abject failure when it comes to the economy,? Mr. Perry said.

For his part, Mr. Perry seemed pleased to take as many questions on the subject that came his way. He paused for a moment, as he reached a patch of shade on a warm afternoon, and told how he would lower the nation?s unemployment rate.

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Pacing the Heart with Light

In the past few years optogenetics, using a combination of genetic manipulation and simple pulses of light, has made it possible to control cells in the brain with astonishing precision?altering brain activity and even behavior in animals.

Now scientists are starting to look beyond the brain as they explore the technology's potential applications. A recent study in Circulation: Arrhythmia & Electrophysiology showed how modified cells that respond to low-energy blue light can be used to stimulate heart tissue to beat. The researchers say this represents a first step toward a new, more efficient and precise kind of pacemaker. Light-sensitive cells could serve as a conductor of the heart's rhythm, creating a biological pacemaker generated from the patient's own cells.

Optogenetics involves genetically engineering cells with light-sensitive proteins, so that scientists can activate them with light. One of the obstacles in using optogenetics as a clinical tool is the need to introduce genes into cells. To get around the problem, the researchers in the current study, led by Emilia Entcheva, a bioengineer at SUNY Stony Brook, decided to take advantages of the tight communication between heart-muscle cells. These cells beat synchronously because they are coupled to one another through cell junctions.

Rather than having to modify every cell in the heart to respond to light, Entcheva says, it's possible to inject a small population of light-sensitive donor cells, and allow those cells to couple with, and orchestrate, the beating of the normal tissue.

To test the approach, the researchers created a line of light-sensitive cells and paired them with heart cells. When stimulated by light, this hybrid cell population contracted in waves that matched the electrical pulses.

Entcheva says she envisions harvesting cells from a patient and genetically altering them to respond to light. By injecting enough modified cells?she estimates that half a million, or a couple of millimeters of tissue, should be enough?it could possible to pace the entire heart. She says that light would use less power than electricity, while offering "unprecedented spatial and temporal resolution"?an advantage in targeting specific parts of the heart. The most likely way to deliver light, she says, would be through thin fiber-optic cables.

The technique has more immediate applications as a research tool, for probing the workings of heart cells or helping test for possible cardiac side effects in drugs. Light, Enthcheva says, would enable more high-throughput screening than current methods, which rely on stimulating cells with electrodes.

Miguel Valderrábano, a cardiologist at the Methodist Hospital in Houston, says that for the past decade scientists have been working on new kinds of biological pacemakers, which usually incorporate cells that are genetically engineered to beat spontaneously in a specific way. The idea of creating cells that instead respond to light is an intriguing new strategy, he says: "It is definitely a conceptual breakthrough in the field of biological pacemaking."

Like other approaches, the technique faces significant hurdles?for instance, making sure the pacemaker cells integrate properly with normal cells. Although biological pacemakers are attractive in theory, they must demonstrate significant advantages over the tried-and-tested electrical devices. "Biological pacemakers have a hard road ahead to outperform regular pacemakers," says Valderrábano.

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Pacing the Heart with Light

In the past few years optogenetics, using a combination of genetic manipulation and simple pulses of light, has made it possible to control cells in the brain with astonishing precision?altering brain activity and even behavior in animals.

Now scientists are starting to look beyond the brain as they explore the technology's potential applications. A recent study in Circulation: Arrhythmia & Electrophysiology showed how modified cells that respond to low-energy blue light can be used to stimulate heart tissue to beat. The researchers say this represents a first step toward a new, more efficient and precise kind of pacemaker. Light-sensitive cells could serve as a conductor of the heart's rhythm, creating a biological pacemaker generated from the patient's own cells.

Optogenetics involves genetically engineering cells with light-sensitive proteins, so that scientists can activate them with light. One of the obstacles in using optogenetics as a clinical tool is the need to introduce genes into cells. To get around the problem, the researchers in the current study, led by Emilia Entcheva, a bioengineer at SUNY Stony Brook, decided to take advantages of the tight communication between heart-muscle cells. These cells beat synchronously because they are coupled to one another through cell junctions.

Rather than having to modify every cell in the heart to respond to light, Entcheva says, it's possible to inject a small population of light-sensitive donor cells, and allow those cells to couple with, and orchestrate, the beating of the normal tissue.

To test the approach, the researchers created a line of light-sensitive cells and paired them with heart cells. When stimulated by light, this hybrid cell population contracted in waves that matched the electrical pulses.

Entcheva says she envisions harvesting cells from a patient and genetically altering them to respond to light. By injecting enough modified cells?she estimates that half a million, or a couple of millimeters of tissue, should be enough?it could possible to pace the entire heart. She says that light would use less power than electricity, while offering "unprecedented spatial and temporal resolution"?an advantage in targeting specific parts of the heart. The most likely way to deliver light, she says, would be through thin fiber-optic cables.

The technique has more immediate applications as a research tool, for probing the workings of heart cells or helping test for possible cardiac side effects in drugs. Light, Enthcheva says, would enable more high-throughput screening than current methods, which rely on stimulating cells with electrodes.

Miguel Valderrábano, a cardiologist at the Methodist Hospital in Houston, says that for the past decade scientists have been working on new kinds of biological pacemakers, which usually incorporate cells that are genetically engineered to beat spontaneously in a specific way. The idea of creating cells that instead respond to light is an intriguing new strategy, he says: "It is definitely a conceptual breakthrough in the field of biological pacemaking."

Like other approaches, the technique faces significant hurdles?for instance, making sure the pacemaker cells integrate properly with normal cells. Although biological pacemakers are attractive in theory, they must demonstrate significant advantages over the tried-and-tested electrical devices. "Biological pacemakers have a hard road ahead to outperform regular pacemakers," says Valderrábano.

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Energy-Harvesting Displays

Adding solar cells to liquid-crystal displays could help recover a significant amount of energy that's ordinarily wasted in powering them. Two research groups have created light filters that double as photovoltaic cells, a trick that could boost the battery life of phones and laptops.

Over 90 percent of the displays sold this year will use liquid-crystal display (LCD) technology. LCDs are, however, tremendously inefficient, converting only about 5 percent of the light produced by a backlight into a viewable image. The LCD in a notebook computer consumes one-third of its power.

This type of screen remains dominant because manufacturers can make LCDs inexpensively on a huge scale. More energy-efficient kinds of displays either are too expensive to manufacture or cannot produce high-quality images. "The LCD is very inefficient, but it works," says Jennifer Colegrove, an analyst at Display Search, a market-research and consulting firm.

Two independent groups?one at the University of California, Los Angeles, the other at the University of Michigan?are tackling two of the biggest culprits of wasted light in LCDs: polarizers and color filters.

Polarizers filter out light that is incompatible with the liquid-crystal shutters in an LCD pixel, accounting for 75 percent of the total light wasted by LCD screens, and conventional color filters toss out two-thirds of the light that hits them. The two research groups have created plastic photovoltaic versions of these two display components, which convert light into electricity.

"We want to take an energy-wasting component that everybody uses and turn it into an energy-saving one," says Yang Yang, professor of materials science and engineering at UCLA. Yang's group created plastic solar cells that can act as polarizers. The researchers simply rub one layer in the solar-cell film with a cloth to align all the molecules in one direction. This alignment turns the cell into a polarizer that converts into electricity some of the light that doesn't pass through.

Yang's work is part of a three-year project being funded by Intel; in the coming year, his team plans to integrate the photovoltaic polarizer into a working display. In a paper published online in the journal Advanced Materials, the team reports that its polarizer can convert into electricity 3 or 4 percent of the light that's normally wasted by a filter. Yang expects to get this up to about 10 percent by tinkering with the materials used.

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Gaming 31 ? OMFG Hats

Why so many Core i7-2600 flavours?

Why so many Core i7-2600 flavours?

Posted on 9th Aug 2011 at 11:35 by Clive Webster with 25 comments

There?s an interesting article over at Ars Technica, titled What processor should I buy: Intel?s crazy pricing makes my head hurt. That might seem a silly question at first: as the author points out, surely you just buy the most expensive CPU in the LGA1155 range. However, Peter Bright is no fool; looking closer at the specs and his requirements, the author struggles to make sense of Intel?s strategy with new features, performance and compatibility.

The problem is due to Bright?s desire to make a future-proof, fast PC that can run Visual Studio and Battlefield 3 easily. A Core i7-2600 is a no-brainer, but there are three flavours, with the S model even running at slower stock speeds to save 30W of power (it Turbo Boosts to the same 3.8GHz as the other i7-2600 CPUs, however).

Then there?s the toss-up between the i7-2600 and the i7-2600K ? the former has some interesting virtualisation and security features that Bright wants, but the latter has a better GPU and the ability to overclock. So which one is better? They both seem compromised and yet there?s a £10 ($23) price difference. The point is really, why has Intel disabled the useful VT-d and the potentially useful TXT logic from the i7-2600K?

Sure, TXT could be seen as a way to introduce hardware-based DRM to a home PC, but as Bright points out, it could also be very useful in preventing rootkits from slaving your PC to their nefarious desire (my melodramatic wording, not his).

Bright finds a solution to his quandary in the Xeon world, where there is a CPU that fits his needs, but then he?s stymied by the lack of Smart Response on official Xeon chipsets. So he?ll have to opt for the not officially supported combination of a Z68 motherboard with a Xeon processor. This should work fine, but for a PC you absolutely rely on for work (I assume) this isn?t a comfortable arrangement.

So why does Intel feel the need to disable potentially useful features from its supposedly top-end CPU when this will slow down uptake? And is the lack of Smart Response technology in any Xeon chipset a tacit admission that it?s not 100 per cent reliable? Conspiracy theories below please!

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Why so many Core i7-2600 flavours?

Why so many Core i7-2600 flavours?

Posted on 9th Aug 2011 at 11:35 by Clive Webster with 25 comments

There?s an interesting article over at Ars Technica, titled What processor should I buy: Intel?s crazy pricing makes my head hurt. That might seem a silly question at first: as the author points out, surely you just buy the most expensive CPU in the LGA1155 range. However, Peter Bright is no fool; looking closer at the specs and his requirements, the author struggles to make sense of Intel?s strategy with new features, performance and compatibility.

The problem is due to Bright?s desire to make a future-proof, fast PC that can run Visual Studio and Battlefield 3 easily. A Core i7-2600 is a no-brainer, but there are three flavours, with the S model even running at slower stock speeds to save 30W of power (it Turbo Boosts to the same 3.8GHz as the other i7-2600 CPUs, however).

Then there?s the toss-up between the i7-2600 and the i7-2600K ? the former has some interesting virtualisation and security features that Bright wants, but the latter has a better GPU and the ability to overclock. So which one is better? They both seem compromised and yet there?s a £10 ($23) price difference. The point is really, why has Intel disabled the useful VT-d and the potentially useful TXT logic from the i7-2600K?

Sure, TXT could be seen as a way to introduce hardware-based DRM to a home PC, but as Bright points out, it could also be very useful in preventing rootkits from slaving your PC to their nefarious desire (my melodramatic wording, not his).

Bright finds a solution to his quandary in the Xeon world, where there is a CPU that fits his needs, but then he?s stymied by the lack of Smart Response on official Xeon chipsets. So he?ll have to opt for the not officially supported combination of a Z68 motherboard with a Xeon processor. This should work fine, but for a PC you absolutely rely on for work (I assume) this isn?t a comfortable arrangement.

So why does Intel feel the need to disable potentially useful features from its supposedly top-end CPU when this will slow down uptake? And is the lack of Smart Response technology in any Xeon chipset a tacit admission that it?s not 100 per cent reliable? Conspiracy theories below please!

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Why so many Core i7-2600 flavours?

Why so many Core i7-2600 flavours?

Posted on 9th Aug 2011 at 11:35 by Clive Webster with 25 comments

There?s an interesting article over at Ars Technica, titled What processor should I buy: Intel?s crazy pricing makes my head hurt. That might seem a silly question at first: as the author points out, surely you just buy the most expensive CPU in the LGA1155 range. However, Peter Bright is no fool; looking closer at the specs and his requirements, the author struggles to make sense of Intel?s strategy with new features, performance and compatibility.

The problem is due to Bright?s desire to make a future-proof, fast PC that can run Visual Studio and Battlefield 3 easily. A Core i7-2600 is a no-brainer, but there are three flavours, with the S model even running at slower stock speeds to save 30W of power (it Turbo Boosts to the same 3.8GHz as the other i7-2600 CPUs, however).

Then there?s the toss-up between the i7-2600 and the i7-2600K ? the former has some interesting virtualisation and security features that Bright wants, but the latter has a better GPU and the ability to overclock. So which one is better? They both seem compromised and yet there?s a £10 ($23) price difference. The point is really, why has Intel disabled the useful VT-d and the potentially useful TXT logic from the i7-2600K?

Sure, TXT could be seen as a way to introduce hardware-based DRM to a home PC, but as Bright points out, it could also be very useful in preventing rootkits from slaving your PC to their nefarious desire (my melodramatic wording, not his).

Bright finds a solution to his quandary in the Xeon world, where there is a CPU that fits his needs, but then he?s stymied by the lack of Smart Response on official Xeon chipsets. So he?ll have to opt for the not officially supported combination of a Z68 motherboard with a Xeon processor. This should work fine, but for a PC you absolutely rely on for work (I assume) this isn?t a comfortable arrangement.

So why does Intel feel the need to disable potentially useful features from its supposedly top-end CPU when this will slow down uptake? And is the lack of Smart Response technology in any Xeon chipset a tacit admission that it?s not 100 per cent reliable? Conspiracy theories below please!

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Source: http://feedproxy.google.com/~r/bit-tech/blog/~3/Mtnh5Y0D4Fg/

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