Neither of Rival Budgets Is Expected to Move in Senate

With the Senate set to vote on both the House-approved measure and a package of much smaller cuts fashioned by the White House and Congressional Democrats, Senator Harry Reid, the Nevada Democrat and majority leader, said the outcome would demonstrate that the Republican proposal had no hope of becoming law.

?We want the American people to know that H.R. 1 is dead,? Mr. Reid told reporters, referring to the House budget.

Neither the House measure nor the Democratic bill appeared anywhere within reach of the 60 votes needed for approval. The votes were forcing difficult decisions, requiring some Republicans to determine whether they could embrace the House cuts and causing some Democrats to examine whether their party?s plan fell short of what was needed.

?I have a lot of concerns about the specific choices made in the House bill,? Senator Susan Collins, Republican of Maine, said Tuesday. ?There are a lot of cuts that I think are ill-advised. There are programs eliminated halfway during the year rather than phased out in an orderly fashion.?

Still, Ms. Collins said she remained undecided, calling the plan proposed by President Obama and Congressional Democrats totally inadequate. Other centrist Republicans indicated they were still making up their minds.

Democrats are hoping the defeat of the House plan will prompt Republicans to give up on the $61 billion figure and move closer to Democrats, who have offered about $10 billion in reductions. The current stopgap measure expires March 18, and members of the House Appropriations Committee on Tuesday were preparing another short-term extension as a contingency if lawmakers again failed to agree on a plan to finance the government through Sept. 30.

The agreement to hold the competing votes Wednesday came after Mr. Reid accused Republicans of trying to back out of a deal struck last week during negotiations with Vice President Joseph R. Biden Jr.

Republicans denied Mr. Reid?s assertion and expressed confidence that the votes would eventually occur even though they suggested that Democrats had not yet come to grips with the difficult steps needed to be taken to address rising deficits.

?It?s time our friends on the other side stop trying to see what they can get away with and actually summon the courage to get our fiscal house in order,? said Senator Mitch McConnell of Kentucky, the Republican leader.

Senator Joe Manchin III, a West Virginia Democrat first elected last fall, took the opportunity Tuesday to ridicule the entire process.

?I might just be a freshmen senator, but I?ll be blunt,? Mr. Manchin said in floor remarks. ?This whole process does not make a lot of sense to me, and I?m afraid it doesn?t make sense to a lot of West Virginians or a lot of our fellow Americans.?

He derided both proposals as ?partisan and unrealistic? and urged the president to play a more assertive role in negotiating a final compromise.

?The truth of the matter,? Mr. Manchin said, ?is this: This debate, as important as it is, will not be decided by House Republicans or Senate Democrats negotiating with each other or past each other. The debate will be decided when the president leads these tough negotiations, and right now that is not happening.?

Mr. Reid defended Mr. Obama, saying: ?I?ve been in touch with the White House literally every day, including weekends. They?re involved in this crisis we have.?

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Only ONE Week to go to enter The Next Web Start Up Rally

There?s just over a month to go until The Next Web Conference 2011 and notably only one week to submit your startup to The Next Web Startup Rally.

The Next Web Startup Rally is an incredible platform to showcase the hottest and most promising startups and we want you there.

The Startup Rally is something our audience particularly look out for. Super fast presentations bring them an overview of what the new hot startups are working on and what the trends are. Many C level attendees love this and for investors the Startup Rally is a great source to source new investments. The overall level of the startups is increasing each year, so for the 6th edition we expect to see great teams, apps and services.

More about The Next Web Conference 2011 on our conference website.

Submit your startup

This year we will give the opportunity to 20 companies in the web and mobile sphere to launch new apps and services on main stage for FREE. It will be harder than ever to make it to the final 20. The 6th edition of the TNW Startup Rally will showcase only the best and most talented teams and companies, with great apps and a bright future ahead of them.

The procedure

1st round: Submissions (deadline March 17 at noon CET) ? 60 companies selected for the 2nd round
2nd round: Video pitch (March 17 ? March 28) ? 35 companies selected for 3rd round
3rd round: Interview round March 22 ? April 5th) 18 companies selected for the finals
Announcement finalists: April 7th
Final round: April 28-29, At The Next Web Conference 2011

Startups number 19 and 20 will be selected by the Jury during the conference from startups that have a booth (get more info on how to get a booth)

Selection criteria:

  • You have to be a company (no side-projects).
  • You have to launch something (your service or a new version of your service). The idea is that journalists and bloggers write about you so you have to bring news to the table.
  • Web/mobile/gaming services, products and new technologies are welcome
  • International focus or aspirations.

Do you want to rock the stage? Submit your startup now!

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Source: http://thenextweb.com/eu/2011/03/09/only-one-week-to-go-to-enter-the-next-web-start-up-rally/

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A Better Disc for Back Repair

The back pain caused by a damaged intervertebral disc often requires surgery, which means either replacing the disc with a plastic or metal implant or removing the disc and fusing the adjacent ones together. A new type of replacement disc?consisting of a scaffold seeded with living cells?could relieve back pain without many of the side effects caused by existing surgical approaches. 

Researchers at the Medical University of South Carolina made a prototype replacement disc by printing an outer scaffold and then seeding the scaffold with living cells. The scaffold closely mimics the intricately layered microstructure of a real intervertebral disc, and is the first step toward making an implant that can perform the same supportive and shock absorbing functions as the original.Compared to the metal and plastic implants used today, an artificial scaffold swathed in living tissue could repair itself, and constant access to blood supply would reduce the risk of infection after surgery.

An intervertebral disc, or IVD, is shaped like a jelly donut, with an soft, elastic center and a tougher, fibrous outer layer. Sandwiched between vertebrae in the spine, the disc defines and supports the spine's movement, holding bones in place while allowing the spine as a whole to bend and twist. The discs also act as shock absorbers, cushioning impacts to the spine. When a disc becomes worn, pressure along the spine is unevenly distributed, and if the vertebrae shift even slightly, they stretch the nerves circling the spine, causing pain. If exercise and physical therapy offer no relief, surgery may be required.

Spinal fusing, however, restricts bending and twisting in the fused section of the spine, so some surgeons make a strong case for the implant method. "None of us were born with fused spines," says Barton Sachs, a professor of orthopedics at the Medical College of South Carolina, who routinely performs disc-implant surgery and who was not connected with the new work. Fusing two bones together can increase the pressure on neighboring segments, wearing out other discs, Sachs says. Not only does an implant preserve motion, but the recovery time from implant surgery is shorter. "It works extremely well," says Sachs. "[Patients] get out of the hospital faster; they get back to their lifestyles faster."

But the implants currently used do not absorb shock. "You're putting in materials that look medieval, and that's the state of current clinical practice," says Robert Mauck, professor of orthopedic surgery and tissue engineering at the University of Pennsylvania. Mauck is working on a competing improvement to disc implants.

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Hardware 19 - The Cockney Cast

Hardware 19 - The Cockney Cast

Posted on 18th Feb 2011 at 10:18 by Podcast with 7 comments

This week's bit-tech and Custom PC podcast is brought to you by Clive, Antony and Paul.

First on the agenda is the continuing Intel Sandy Bridge saga, and what motherboard manufacturers are doing to sort it out. We also comment on MSI's returns strategy, which the company announced on Wednesday.

Next we make some time to talk about the gorgeous Silverstone FT03. It's a pretty peculiar case due to its inverted design, but it's always refreshing to see manufactures taking a different approach.

Finally, Antony gives us a sneaky look at the CPU cooler group test from the latest issue of Custom PC, which went on sale at newsagents yesterday. Make sure you pick up a copy if you want to see which new CPU coolers offer the best combination of cooling and value.


As always, we've also set up our weekly competition, although there's a slightly different twist on it this week. The lucky winner will be able to get their hands on a Mionix Propus 380 mousepad, which will provide the perfect tracking surface for whichever mouse you choose to use.

As ever, the bit-tech hardware podcast features music by Brad Sucks, and was recorded on Shure microphones. You can download the podcast direct, listen in-browser or subscribe through iTunes using the links below. Also, be sure to let us know your thoughts about the discussion in the forums.

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Making Genome Sequencing Part of Clinical Care

Researchers at the Medical College of Wisconsin are taking pioneering steps to make whole-genome sequencing a standard part of diagnostic testing for children with rare inherited disorders not easily diagnosed by traditional methods. The technology has come far in the decade since the $3 billion human genome project was published?so far, in fact, that a health insurer has offered to cover the sequencing in cases where it would be cheaper than conventional genetic testing.

Whole-genome sequencing?reading a patient's entire DNA code?now costs about the same as sequencing just a few genes through commercial diagnostic tests, says Howard Jacob, director of the college's Human and Molecular Genetics Center.

Over the last year, whole-genome sequencing has proved its medical worth. Scientists have been able to pinpoint the genetic mutations underlying a number of rare, difficult-to-diagnose diseases, in some cases resulting in life-saving treatments. But despite the medical benefits, these efforts have so far been limited to the research realm.

"Howard wants to make this a routine clinical test," says Nicholas Schork, director of bioinformatics and biostatistics at the Scripps Translational Science Institute. "He has gone the extra mile to convince regulatory and legal people at his institution that this should be part of the diagnostic."

The Wisconsin team garnered international attention in December when researchers published their effort to diagnose Nicholas Volker, a six-year-old with a severe form of inflammatory bowel disease that failed to respond to treatment. By the age of three, Nicholas had already undergone 100 surgeries to try to repair his damaged digestive system. He also had symptoms of an immune disorder, and physicians were considering a cord-blood transplant?a transfusion of stem cells from umbilical cord blood, similar to a bone-marrow transplant?to reboot his immune system. But without a definitive diagnosis, they were hesitant to undertake this procedure, which carries a significant risk of death.

Jacob took on Nicholas's case thanks to a desperate letter from his physician. After sequencing the child's genome, Jacob's team identified a mutation on the X chromosome that has been linked to an inherited immune disorder. The mutation is unique, not found in any of the other human?or animal?genomes sequenced to date. With the new diagnosis in hand, doctors performed the cord-blood transplant. Eight months later Nicholas is out of the hospital and doing well.

The Volker case was considered a research project. But Jacob felt strongly that genome sequencing should be part of the ordinary diagnostic arsenal for children with rare inherited disorders. He has spent the last year and a half trying to transform what has been a promising medical technology into a routine diagnostic, with standard procedures and clinically certified tests. Five hundred pages of forms later, "we created a separate infrastructure for doing purely clinical cases," says Jacob, who presented details of his efforts last week at the Future of Genomic Medicine conference in San Diego, California.

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Adobe releases Flash 10.3 beta for Windows, Mac, and Linux

LimeWire reaches settlement with music publishers

The music industry has reached a settlement with LimeWire, concluding a nine-month legal battle. Eight music publishers including EMI, Sony, Universal and Warner joined forces last June to accuse the peer-to-peer filesharing service of knowingly and deliberately infringing copyrighted material.

The National Music Publishers Association originally sought $150,000 for each song shared illegally on LimeWire, which would have easily racked up to hundreds of millions of dollars or more. It's unclear how much, if any cash will trade hands in the settlement as the terms haven't been made public.


A spokeswoman for the publishers has simply said that both sides have "worked hard to achieve a settlement that is a good result for all involved." The court filing also revealed that each party will pay for its own legal fees, so perhaps things haven't ended too poorly on LimeWire's end.

LimeWire founder Mark Gorton was found guilty of copyright infringement, induced copyright infringement, and unfair competition last May in a suit against the recording industry. The service was shut down in October and is still defending itself from more than $1 billion in claimed damages.

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Source: http://www.techspot.com/news/42728-limewire-reaches-settlement-with-music-publishers.html

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Political Memo: G.O.P. Voters Are Ready for the 2012 Race. Now Somebody Tell the Candidates.

Republicans have been far more eager to criticize President Obama than to formally jump into the race and start jockeying for the right to challenge him. But their hesitation, or strategic patience, has done little to slow the early stages of the party?s nominating contest.

Things reached a preseason high Monday when six prospective Republican contenders ? at least three of whom are viewed as long shots ? were drawn to Iowa. An evening candidates? forum was billed as the first such gathering of the year, filling a church auditorium with Republican activists and a crush of reporters so large that it seemed like election eve.

A curious trend is emerging in the early days of the 2012 presidential race: Republican voters are searching for candidates far more aggressively than candidates are searching for voters.

Four years ago, nearly all of the contenders from both parties were already in the race by now. This time around, none of the big names have plunged fully in. Newt Gingrich, the former House speaker, became the first major candidate to start raising money last week, but kept his options open, a tease that left some Republicans wondering whether he was truly committed to, and ready for, a campaign.

Whether it is because they see Mr. Obama as a more formidable rival than they expected, or because they want to delay the scrutiny that comes with a formal declaration, or because they want to see the field gel before making any final decisions, the most prominent of potential candidates are remaining coy for now.

But coming off major Republican gains last fall and with the Tea Party movement helping to energize the party at the grass-roots level, the entrepreneurial spirit of Republican activists in early-voting states is alive and they are going to great lengths to try to kick-start the race.

At Point of Grace Church, which sits on a sprawling campus in this western suburb of Des Moines, more than 1,000 Republicans turned out to begin taking a measure of some of the party?s contenders at a forum sponsored by the Iowa Faith and Freedom Coalition. The evening at the megachurch took on the feeling of a religious service, including passing the envelope for attendees to make contributions to the group.

The event not only marked the unofficial opening of the Iowa caucus campaign, it also provided an early window into the balance that candidates will seek to strike as they navigate the demands of fiscal and social conservatives. Some of the biggest names in the Republican Party were not on hand, which left some in the audience wondering if the party was taking too leisurely an approach on the difficult task of defeating a sitting president.

?Iowa voters want to meet the candidates,? said Gov. Terry Branstad, a Republican. ?They want to be able to ask them the tough questions; they want to make their own evaluation and decision.?

Mr. Gingrich, former Gov. Tim Pawlenty of Minnesota and former Senator Rick Santorum of Pennsylvania delivered their pitches, pledging to keep social issues like opposing abortion rights and gay marriage central. But the slow-to-develop race has also created an opening for an array of political figures and celebrities to enjoy a moment in the spotlight.

Sarah Palin, Mike Huckabee and Mitt Romney declined invitations to come to Iowa on Monday. But Herman Cain, a former chief executive at Godfather?s Pizza, and former Gov. Buddy Roemer of Louisiana made their debuts on the 2012 campaign stage in an evening that was broadcast live on C-Span.

?I have a breaking news announcement for President Obama,? Mr. Cain said. ?The United States of America is not going to become the United States of Europe ? not on our watch.?

Mr. Roemer vowed to cap his campaign contributions at $100. He introduced himself as a fighting outsider, saying: ?The nation is hurting and Washington, D.C., is a boomtown. How does that grab you??

The Iowa prospecting also included a visit from Representative Ron Paul of Texas, who appeared at a separate event. They were all joined in the flurry of news coverage by a top aide to Donald Trump, who flew to Des Moines and staged a news conference with a Trump plane in the background.

?Hopefully he decides to run in June,? said Michael Cohen, executive vice president of the Trump organization.

The Iowa caucuses and the New Hampshire primary, the contests that traditionally open the presidential nominating season, will not take place until early next year. But the first Republican debates are less than two months away, creating a sense of anxiety among some voters who are eager to find the strongest challenger to Mr. Obama.

As he walked from the church, mingling with people from the crowd, Steve Scheffler, chairman of the Iowa Faith and Freedom Coaltion, said that time was running short for candidates to open their campaigns and begin making their case to Iowans.

?At some point in the next month or two, they are going to have to come here and plant their flag or caucusgoers will be looking for other alternatives,? said Mr. Scheffler, who is also a member of the Republican National Committee. ?Caucusgoers expect to be talked to and listened to.?

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Please Update Your Status at Work

Some companies actually want their employees to blog, tweet, and update their social-networking profiles at work?as long as they're doing it on corporate-purchased software.

Three years ago, the information management company EMC began encouraging employees to spend time on internal social networks discussing their extracurricular interests. "We have people talking about photography, and art, rock climbing?you name it," says Jamie Pappas, whose title speaks volumes: she is manager of enterprise social-media engagement strategy.

EMC had something in mind beyond connecting all its motorcycle enthusiasts. The management wanted to test new "social business software" from Jive, a company that runs online forums and social-networking and collaboration software for businesses.

"The thinking really was that employees really want to come together around a topic, and they're worried about saying something wrong if it's about a [work] project," Pappas says. "So those social conversations were sort of like icebreakers. It helped people get in there and then feel comfortable jumping into the business conversation."

When companies get too big, opportunities for collaboration can diminish. Individual employees looking for a colleague with expertise on a particular topic can struggle to find the right person. E-mail is little help: employees' in-boxes are deluged. Corporate memory of sales leads or customer service solutions can get buried.

In hopes of cutting through the noise, Jive offers a wide-ranging platform for collaboration, competing with the likes of IBM and Oracle. It offers applications to connect colleagues and projects the way Facebook, Twitter, and Web forums connect fan bases and friends. Employees set up profiles, blogs, groups, and Facebook-style "walls." All this interaction happens behind the corporate firewall but is accessible by internal search programs. In turn, these programs work with software that companies already have in place, including customer relationship management (CRM) programs, Microsoft's Sharepoint, and software for human resources, supply chain management, and accounting.

At EMC, instead of starting long e-mail threads, employees can check updates about a project on a Jive page, search for relevant materials, and download the files as they need them. Sales representatives looking for insight about a competitor can query the "competitive community" on EMC's internal social network and get an answer as they walk to a client meeting, Pappas says. The company also now uses Jive's tools externally, to augment user-support forums and to create community or "affinity" pages for clients that use EMC software.

Collaboration tools with origins in the consumer world, such as instant messaging, have often met with resistance from IT departments. But Stowe Boyd, an analyst and advisor to companies building such applications, says business-focused social-networking software is growing much faster than earlier tools. Christopher Morace, Jive's senior vice president of business development, credits the increased popularity of Facebook. When Jive started selling its social business software in 2007, some potential customers were wary of adding more tasks to the workday. But now, Morace says, he doesn't need to explain that with these tools, a person can realistically keep track of multiple conversations and engage hundreds of contacts.

Jive hopes to become something like a Facebook in business?a widely used platform on which many kinds of applications are hosted. The company is building a developer community and allowing third parties to write apps to work with its software. "When push comes to shove," Morace says, "when this market becomes really competitive, we decided we are really good at being the modern platform."

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Political Memo: G.O.P. Voters Are Ready for the 2012 Race. Now Somebody Tell the Candidates.

Republicans have been far more eager to criticize President Obama than to formally jump into the race and start jockeying for the right to challenge him. But their hesitation, or strategic patience, has done little to slow the early stages of the party?s nominating contest.

Things reached a preseason high Monday when six prospective Republican contenders ? at least three of whom are viewed as long shots ? were drawn to Iowa. An evening candidates? forum was billed as the first such gathering of the year, filling a church auditorium with Republican activists and a crush of reporters so large that it seemed like election eve.

A curious trend is emerging in the early days of the 2012 presidential race: Republican voters are searching for candidates far more aggressively than candidates are searching for voters.

Four years ago, nearly all of the contenders from both parties were already in the race by now. This time around, none of the big names have plunged fully in. Newt Gingrich, the former House speaker, became the first major candidate to start raising money last week, but kept his options open, a tease that left some Republicans wondering whether he was truly committed to, and ready for, a campaign.

Whether it is because they see Mr. Obama as a more formidable rival than they expected, or because they want to delay the scrutiny that comes with a formal declaration, or because they want to see the field gel before making any final decisions, the most prominent of potential candidates are remaining coy for now.

But coming off major Republican gains last fall and with the Tea Party movement helping to energize the party at the grass-roots level, the entrepreneurial spirit of Republican activists in early-voting states is alive and they are going to great lengths to try to kick-start the race.

At Point of Grace Church, which sits on a sprawling campus in this western suburb of Des Moines, more than 1,000 Republicans turned out to begin taking a measure of some of the party?s contenders at a forum sponsored by the Iowa Faith and Freedom Coalition. The evening at the megachurch took on the feeling of a religious service, including passing the envelope for attendees to make contributions to the group.

The event not only marked the unofficial opening of the Iowa caucus campaign, it also provided an early window into the balance that candidates will seek to strike as they navigate the demands of fiscal and social conservatives. Some of the biggest names in the Republican Party were not on hand, which left some in the audience wondering if the party was taking too leisurely an approach on the difficult task of defeating a sitting president.

?Iowa voters want to meet the candidates,? said Gov. Terry Branstad, a Republican. ?They want to be able to ask them the tough questions; they want to make their own evaluation and decision.?

Mr. Gingrich, former Gov. Tim Pawlenty of Minnesota and former Senator Rick Santorum of Pennsylvania delivered their pitches, pledging to keep social issues like opposing abortion rights and gay marriage central. But the slow-to-develop race has also created an opening for an array of political figures and celebrities to enjoy a moment in the spotlight.

Sarah Palin, Mike Huckabee and Mitt Romney declined invitations to come to Iowa on Monday. But Herman Cain, a former chief executive at Godfather?s Pizza, and former Gov. Buddy Roemer of Louisiana made their debuts on the 2012 campaign stage in an evening that was broadcast live on C-Span.

?I have a breaking news announcement for President Obama,? Mr. Cain said. ?The United States of America is not going to become the United States of Europe ? not on our watch.?

Mr. Roemer vowed to cap his campaign contributions at $100. He introduced himself as a fighting outsider, saying: ?The nation is hurting and Washington, D.C., is a boomtown. How does that grab you??

The Iowa prospecting also included a visit from Representative Ron Paul of Texas, who appeared at a separate event. They were all joined in the flurry of news coverage by a top aide to Donald Trump, who flew to Des Moines and staged a news conference with a Trump plane in the background.

?Hopefully he decides to run in June,? said Michael Cohen, executive vice president of the Trump organization.

The Iowa caucuses and the New Hampshire primary, the contests that traditionally open the presidential nominating season, will not take place until early next year. But the first Republican debates are less than two months away, creating a sense of anxiety among some voters who are eager to find the strongest challenger to Mr. Obama.

As he walked from the church, mingling with people from the crowd, Steve Scheffler, chairman of the Iowa Faith and Freedom Coaltion, said that time was running short for candidates to open their campaigns and begin making their case to Iowans.

?At some point in the next month or two, they are going to have to come here and plant their flag or caucusgoers will be looking for other alternatives,? said Mr. Scheffler, who is also a member of the Republican National Committee. ?Caucusgoers expect to be talked to and listened to.?

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Source: http://feeds.nytimes.com/click.phdo?i=e84baae3aeac7a998c13c38c02060340

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