Founder2be is like Internet dating for tech entrepreneurs looking for co-founders

Ask entrepreneurs about important early factors in the success of their startups and many will say that finding a really good co-founder is key. Founder2be is an organisation looking to make that process easier by taking an approach similar to online dating.

The website acts as a matchmaking service for entrepreneurs. Founder2be users create profiles, sharing information like their location; skills; availability; previous projects; startup and fund-raising experience; ability to contribute seed funding, and co-founder preferences. The site then offers up potential suitable matches. Users can also post up product ideas, helping to find a match with he right interests and skills.

Although launched in Finland, Founder2be is taking a global approach by partnering with other organisations in a Global Alliance Program. This is designed to help co-founders meet each other and form startups within business incubators, accelerators, student societies and other entrepreneurship organisations. Current partners are situated across Europe, plus a number of others doted around the world in places such as South Korea and Australia.

Founder2be was launched earlier this year by Oliver Bremer (a former Nokia employee mentioned in our story about how the mobile giant?s decline is spurring a new wave of startups in Finland) and Frank Haubenschild. So far, two companies have emerged from the programme ? business productivity outfit Ziliot, plus another currently in stealth mode.

The organisation is currently looking to find new partners in Africa and Europe, including the UK. It is also planning a series of offline events.

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Source: http://thenextweb.com/eu/2011/06/27/founder2be-is-like-internet-dating-for-tech-entrepreneurs-looking-for-co-founders/

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Facebook May Mobilize on Web Apps

Blog - Prion Disease: Secret of Immunity Revealed

A prion is a misshapen protein that acts like an infectious agent (hence the name, which comes from the words protein and infection).

Prions cause a number of fatal diseases such as mad cow disease in cattle, scrapie in sheep and kuru and Creutzfeldt-Jakob disease (CJD) in humans. There is no cure and potential treatments are highly speculative.

In recent years, however, biologists have discovered several animals that are immune to prion diseases. These include horses, dogs and rabbits. Nobody knows why.

But a great deal of effort is being expended to find out. In the last couple of years, molecular biologists have identified the structure of the proteins in these immune species that in other animals cause prion disease. The obvious question is this: what's the difference?

Today, we have an answer thanks to an impressive set of molecular simulations carried out by Jiapu Zhang at the The University of Ballarat in Australia.

Zhang has simulated how these proteins change shape as their temperature and pH changes.

His conclusion is that the immune proteins are more stable than the others because of a salt bridge that connects two parts of the immune proteins "like a taught bow string". This prevents them from misfolding into an infectious form.

That's an interesting result because it immediately provides a therapeutic target to aim at. "This salt bridge might be a potential drug target for prion diseases," says Zhang.

The idea is that it might be possible to stabilise prion proteins in cattle, sheep and humans using an artificial salt bridge, similar to the one in dogs, horses and rabbits.

A long shot but certainly worth pursuing.

Ref: arxiv.org/abs/1106.4628: The Nature Of The Infectious Agents: PrP Models Of Resistant Species To Prion Diseases (Dog, Rabbit And Horses)


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Beyond New York, Gay Marriage Faces Hurdles

But the movement?s success here could prove difficult to replicate. Twenty-nine states have constitutional bans on same-sex marriage, while 12 others have laws against it. And many of those states where support for same-sex marriage is high have already acted on the issue.

Officials at several gay-rights organizations said they would seek to move quickly in Maryland, where legislation to legalize same-sex marriage was shelved in February by Democratic leaders concerned that it lacked the support to pass.

Advocates also said they hoped to resuscitate a marriage bill that died in the Rhode Island legislature this year.

Gay-rights groups are likely to seek ballot initiatives next year to overturn bans on same-sex marriage in Maine, where the Legislature approved a same-sex marriage law in 2009 that voters almost immediately turned back, and in Oregon.

Advocates hope, in the longer term, to win the legalization of same-sex marriage in Delaware and New Jersey, two states where Democrats control the legislatures, as well as in Pennsylvania.

?The fundamental issue here is American public opinion,? said Fred Sainz, a spokesman for the Human Rights Campaign, a national gay-rights organization. ?The outcome in New York will be tremendously impactful in shaping the rest of the debate.?

The vote on Friday in New York, home of the nation?s economic and cultural capital, carries enormous symbolic importance for the same-sex-marriage movement, particularly after its defeat, with Proposition 8, three years ago in California.

New York is now the sixth and largest state in the country where gay couples will be able to wed legally; when the state?s law goes into effect in late July, twice as many Americans will live in jurisdictions where same-sex marriage is permitted.

But beyond symbolism, gay-rights advocates said that New York had provided them with a new political model.

?They?ve shown a way to actually get a bill through a Legislature,? said Richard S. Madaleno Jr., a Democratic state senator in Maryland and sponsor of the marriage bill that was shelved. ?And I think we?re going to use some of the same lessons, the same tactics, in Maryland over the next six months.?

Mr. Madaleno, in a telephone interview on Saturday, said Maryland gay-rights advocates had failed to mount the kind of vigorous, multimillion-dollar grass-roots campaign that their allies in New York ran this spring. Nor had they pressed the state?s Democratic governor, Martin O?Malley, to deploy his own political capital and muscle on their behalf, as Gov. Andrew M. Cuomo did in New York.

?We had not done as good a job beating the bushes in districts as they did in New York,? Mr. Madaleno said. ?Our hope is that not only will our legislature take a cue from our colleagues in Albany, but that our governor might as well.?

Perhaps the most striking shift in Albany was the role played by Republican lawmakers in the State Senate. Republican senators voted unanimously against same-sex marriage two years ago, when they were in the minority; this year, with a majority in the chamber, they not only allowed the marriage bill to come to the floor, but also provided the final votes necessary to approve it. The decision by 4 Republicans to join 29 Democrats to push the measure through the 62-seat Senate marked the first time in the nation that a legislative body controlled by Republicans approved either same-sex marriages or civil unions, advocates said.

That shift was precipitated by the emergence of a growing constituency of pro-gay-marriage operatives and donors in the Republican Party, whose direction on social issues is still largely set by its culturally conservative base.

?There is an important change going on among Republicans and conservatives,? said Kenneth B. Mehlman, a former chairman of the Republican National Committee.

Mr. Mehlman, who acknowledged his own homosexuality after his tenure at the national committee had ended, was among a group of Republicans who helped raise money from prominent Republican donors to support the same-sex marriage effort in Albany. Those donors underwrote much of the cost of the same-sex marriage advocates? advertising and lobbying campaigns.

Among increasing numbers of conservatives and Republicans, he said, there is the conviction ?that freedom to marry is consistent with conservative values.?

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Blog - Prion Disease: Secret of Rabbit Immunity Revealed

A prion is a misshapen protein that acts like an infectious agent (hence the name, which comes from the words protein and infection).

Prions cause a number of fatal diseases such as mad cow disease in cattle, scrapie in sheep and kuru and Creutzfeldt-Jakob disease (CJD) in humans. There is no cure and potential treatments are highly speculative.

In recent years, however, biologists have discovered several animals that are immune to prion diseases. These include horses, dogs and rabbits. Nobody knows why.

But a great deal of effort is being expended to find out. In the last couple of years, molecular biologists have identified the structure of the proteins in these immune species that in other animals cause prion disease. The obvious question is this: what's the difference?

Today, we have an answer thanks to an impressive set of molecular simulations carried out by Jiapu Zhang at the The University of Ballarat in Australia.

Zhang has simulated how these proteins change shape as their temperature and pH changes.

His conclusion is that the immune proteins are more stable than the others because of a salt bridge that connects two parts of the immune proteins "like a taught bow string". This prevents them from misfolding into an infectious form.

That's an interesting result because it immediately provides a therapeutic target to aim at. "This salt bridge might be a potential drug target for prion diseases," says Zhang.

The idea is that it might be possible to stabilise prion proteins in cattle, sheep and humans using an artificial salt bridge, similar to the one in dogs, horses and rabbits.

A long shot but certainly worth pursuing.

Ref: arxiv.org/abs/1106.4628: The Nature Of The Infectious Agents: PrP Models Of Resistant Species To Prion Diseases (Dog, Rabbit And Horses)


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Beyond New York, Gay Marriage Faces Hurdles

But the movement?s success here could prove difficult to replicate. Twenty-nine states have constitutional bans on same-sex marriage, while 12 others have laws against it. And many of those states where support for same-sex marriage is high have already acted on the issue.

Officials at several gay-rights organizations said they would seek to move quickly in Maryland, where legislation to legalize same-sex marriage was shelved in February by Democratic leaders concerned that it lacked the support to pass.

Advocates also said they hoped to resuscitate a marriage bill that died in the Rhode Island legislature this year.

Gay-rights groups are likely to seek ballot initiatives next year to overturn bans on same-sex marriage in Maine, where the Legislature approved a same-sex marriage law in 2009 that voters almost immediately turned back, and in Oregon.

Advocates hope, in the longer term, to win the legalization of same-sex marriage in Delaware and New Jersey, two states where Democrats control the legislatures, as well as in Pennsylvania.

?The fundamental issue here is American public opinion,? said Fred Sainz, a spokesman for the Human Rights Campaign, a national gay-rights organization. ?The outcome in New York will be tremendously impactful in shaping the rest of the debate.?

The vote on Friday in New York, home of the nation?s economic and cultural capital, carries enormous symbolic importance for the same-sex-marriage movement, particularly after its defeat, with Proposition 8, three years ago in California.

New York is now the sixth and largest state in the country where gay couples will be able to wed legally; when the state?s law goes into effect in late July, twice as many Americans will live in jurisdictions where same-sex marriage is permitted.

But beyond symbolism, gay-rights advocates said that New York had provided them with a new political model.

?They?ve shown a way to actually get a bill through a Legislature,? said Richard S. Madaleno Jr., a Democratic state senator in Maryland and sponsor of the marriage bill that was shelved. ?And I think we?re going to use some of the same lessons, the same tactics, in Maryland over the next six months.?

Mr. Madaleno, in a telephone interview on Saturday, said Maryland gay-rights advocates had failed to mount the kind of vigorous, multimillion-dollar grass-roots campaign that their allies in New York ran this spring. Nor had they pressed the state?s Democratic governor, Martin O?Malley, to deploy his own political capital and muscle on their behalf, as Gov. Andrew M. Cuomo did in New York.

?We had not done as good a job beating the bushes in districts as they did in New York,? Mr. Madaleno said. ?Our hope is that not only will our legislature take a cue from our colleagues in Albany, but that our governor might as well.?

Perhaps the most striking shift in Albany was the role played by Republican lawmakers in the State Senate. Republican senators voted unanimously against same-sex marriage two years ago, when they were in the minority; this year, with a majority in the chamber, they not only allowed the marriage bill to come to the floor, but also provided the final votes necessary to approve it. The decision by 4 Republicans to join 29 Democrats to push the measure through the 62-seat Senate marked the first time in the nation that a legislative body controlled by Republicans approved either same-sex marriages or civil unions, advocates said.

That shift was precipitated by the emergence of a growing constituency of pro-gay-marriage operatives and donors in the Republican Party, whose direction on social issues is still largely set by its culturally conservative base.

?There is an important change going on among Republicans and conservatives,? said Kenneth B. Mehlman, a former chairman of the Republican National Committee.

Mr. Mehlman, who acknowledged his own homosexuality after his tenure at the national committee had ended, was among a group of Republicans who helped raise money from prominent Republican donors to support the same-sex marriage effort in Albany. Those donors underwrote much of the cost of the same-sex marriage advocates? advertising and lobbying campaigns.

Among increasing numbers of conservatives and Republicans, he said, there is the conviction ?that freedom to marry is consistent with conservative values.?

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TNW Weekend Roundup: All of the weekend?s biggest stories

If you didn?t have the opportunity to catch up on your daily fix of technology bits and bites over the weekend, the TNW Weekend Roundup will bring you quickly up to speed with what happened on Saturday and Sunday, linking you to the most popular and discussed stories here on The Next Web and elsewhere.

Google Health has six months to live, so now who?s going to disrupt healthcare?

Google is closing its open platform Health service due to failure to gain enough traction to be sustainable in the longterm.

As Google notes in today?s announcement, ?We?ve observed that Google Health is not having the broad impact that we hoped it would. There has been adoption among certain groups of users like tech-savvy patients and their caregivers, and more recently fitness and wellness enthusiasts. But we haven?t found a way to translate that limited usage into widespread adoption in the daily health routines of millions of people.? Read More.

Interview with FanBridge: Social media smarts for musicians

The days of lament over album sales are long gone. Bands have gotten with the times, and are constantly seeking new, innovative ways to reach fans in the digital age. Check out our story on BlueBrain, a Washington, D.C. based band who put out the first musical album that?s also a location aware iPhone app. Now that?s epic innovation! Being tech savvy and jumping on the social media train, like any smart brand, is essential for bands. It?s simply where the party is. Read More.

Why Turntable.fm is the most exciting social service of the year

It?s emerged out of nowhere to become one of the coolest sites on the Web in a matter of weeks, but what?s the story behind Turntable.fm, what?s so great about it and where is it going?

A service amassing a reported 140,000 users in its first month is nothing to be sniffed at at any time. A service that hasn?t courted the press at all, growing entirely virally, hitting that figure in a month is something that demands closer inspection. Read More.

LulzSec?s ?final? data release claims to include AOL, AT&T, FBI information and more

Hacker group LulzSec, it appears, is through with its ?anarchic lulz?, announcing today via Pastebin (of course) that it?s quitting after fifty days of activity.

?For the past 50 days we?ve been disrupting and exposing corporations, governments, often the general population itself, and quite possibly everything in between, just because we could,? the group notes. ?While we are responsible for everything that The Lulz Boat is, we are not tied to this identity permanently.? Read More.

Breaking down the magical success of the iPad

Magical. The word has been used hundreds of times in Apple?s marketing to describe its products, but really took prominence with the introduction of the iPad. When Apple CEO Steve Jobs took the stage in early 2010 to introduce what we all knew at that point to be some sort of new tablet product, one of the first adjectives he used for it was ?magical?. Read More.

The rise of Major League Gaming and the future of esports

Esports is now no laughing matter as companies that cater to gamers are joining a cast of A-list brands in sponsoring massive competitive leagues around the world that are sporting five and six figure prize pools. Read More.

Does Creative Commons make us more creative?

Creative Commons encourages artists and creators to share their work under a Creative Commons License. This is where it starts to get a bit complicated because there are several permutations to the license, and you have to understand each one before deciding which one is right for you. Read More.

Are Facebook and Twitter now too mainstream to be cool?

When you see something special for the first time you just get that feeling in your stomach that you are in at the ground level and you are bursting with excitement waiting for the rest of the world to find out. People used to have that same feeling with Twitter and before that with Facebook.

We?ve hit a very different situation now where the two biggest social networks have very much hit the mainstream and for the first time in my recollection the press is starting to turn a little on them both? Read More.

50 days of Lulz: The life and times of LulzSec

In 50 days, the group dominated headlines of nearly every print and online news agency across the world, distanced itself from the arrest of Ryan Cleary by the Metropolitan Police and antagonized whoever it could, simply ?for the lulz?. With each day, we got to know more about the group; what its motivations were, how it was able to steal so much data and the identities of its members were supposedly revealed on a number of occasions.

With the group now apparently disbanded, here?s a look back at 50 days of LulzSec?s exploits. Read More.

What Would Colonization of the Final Frontier Look Like?

Space colonization is something that people have dreamed about since the moon landing, and is in fact considered a priority for the future of mankind by leading scientists.

Aerospace advances, submarines that humans can survive in for months at a time autonomously and experiments like the Biodome have all led to uncovering pieces of the puzzle. Read More.

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Diplomatic Memo: Taking a Risk With Taliban Negotiations, Even if the Talks Are Real This Time

Among the many reasons: It is not clear that the Taliban want to negotiate, or who even represents the organization. The Afghan president has distanced himself from the talks, raising doubts about whether the country?s leaders would be open to a reprise of Taliban involvement in the political process.

And Pakistan, the vital third leg of negotiations because of its ties to the Taliban, is increasingly a wild card because of recent strains with the United States over the drone assaults on terrorist suspects inside Pakistan.

Mr. Obama told soldiers at Fort Drum, N.Y., on Thursday that ?because of you, there are signs that the Taliban may be interested in figuring out a political settlement, which ultimately is going to be critical for consolidating that country.?

So far, however, those signs are hazy at best, according to officials and diplomats.

American officials have participated in three meetings this year with an English-speaking Afghan who was once a personal assistant to the renegade Taliban leader Mullah Muhammad Omar. Those meetings, in Germany and Qatar, appear to have accomplished little more than confirming the man?s identity, and perhaps not even that, according to officials familiar with the talks, all of whom requested anonymity to discuss the secret talks.

Adding another layer of complexity to the already murky effort, the English-speaking Afghan, Tayeb Agha, who was an aide to Mullah Omar during the Taliban?s rise to power, was arrested by Pakistani authorities last year and then released, leading American officials to assume that he is negotiating on behalf of the Taliban with the blessings of the Pakistani authorities.

?We?re at that stage where it?s very confusing,? one senior administration official said, adding that the meetings could not even be called ?talks? at this stage, let alone ?peace talks.?

The wariness in part reflects the fact that the administration has been badly embarrassed by previous diplomatic efforts. An Afghan was given substantial sums of cash last year and was flown on a NATO aircraft in the belief that he was a Taliban envoy, but he turned out to be an impostor.

Even so, the renewed diplomatic push signals a significant shift in Mr. Obama?s strategy since he came to office in 2009 and increased American forces in Afghanistan to nearly 100,000 troops, from 34,000, in an effort to crush a resurgent Taliban insurgency.

While the military has secured parts of the country and bolstered the Afghan government?s security forces, the administration now recognizes that a final American withdrawal depends on a political settlement with the Taliban, a fundamentalist Islamic movement equated closely with the murderous ideology of Al Qaeda. The attacks of Sept. 11, 2001, were orchestrated by Al Qaeda under the Taliban?s protection.

The administration has imposed significant conditions for any reconciliation with the Taliban. The movement?s leaders must disarm, sever ties with Al Qaeda?s remaining leadership, recognize the government in Afghanistan and accept the country?s Constitution, including basic rights for women, who were severely repressed when the Taliban governed the country in the 1990s.

It is uncertain whether the Taliban or even parts of its leadership are willing to accept such conditions, and many experts are deeply skeptical.

?There really can?t be a deal on the core red lines, because that?s what red lines are,? Michael O?Hanlon, a senior fellow at the Brookings Institution, said of the conditions, using the diplomatic term for nonnegotiable demands.

The diplomatic effort is being led by Marc Grossman, who replaced Richard C. Holbrooke as special envoy to Afghanistan and Pakistan after Mr. Holbrooke died in December.

Thom Shanker contributed reporting.

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Behind N.Y. Gay Marriage, an Unlikely Mix of Forces

Over tuna and turkey sandwiches, the advisers explained that New York?s Democratic governor was determined to legalize same-sex marriage and would deliver every possible Senate vote from his own party.

Would the donors win over the deciding Senate Republicans? It sounded improbable: top Republican moneymen helping a Democratic rival with one of his biggest legislative goals.

But the donors in the room ? the billionaire Paul Singer, whose son is gay, joined by the hedge fund managers Cliff Asness and Daniel Loeb ? had the influence and the money to insulate nervous senators from conservative backlash if they supported the marriage measure. And they were inclined to see the issue as one of personal freedom, consistent with their more libertarian views.

Within days, the wealthy Republicans sent back word: They were on board. Each of them cut six-figure checks to the lobbying campaign that eventually totaled more than $1 million.

Steve Cohen, the No. 2 in Mr. Cuomo?s office and a participant in the meeting, began to see a path to victory, telling a colleague, ?This might actually happen.?

The story of how same-sex marriage became legal in New York is about shifting public sentiment and individual lawmakers moved by emotional appeals from gay couples who wish to be wed.

But, behind the scenes, it was really about a Republican Party reckoning with a profoundly changing power dynamic, where Wall Street donors and gay-rights advocates demonstrated more might and muscle than a Roman Catholic hierarchy and an ineffective opposition.

And it was about a Democratic governor, himself a Catholic, who used the force of his personality and relentlessly strategic mind to persuade conflicted lawmakers to take a historic leap.

?I can help you,? Mr. Cuomo assured them in dozens of telephone calls and meetings, at times pledging to deploy his record-high popularity across the state to protect them in their districts. ?I am more of an asset than the vote will be a liability.?

Over the last several weeks, dozens of lawmakers, strategists and advocates described the closed-door meetings and tactical decisions that led to approval of same-sex marriage in New York, about two years after it was rejected by the Legislature. This account is based on those interviews, most of which were granted on the condition of anonymity to describe conversations that were intended to be confidential.

?I Have to Do This?

Mr. Cuomo was diplomatic but candid with gay-rights advocates in early March when he summoned them to the Capitol?s Red Room, a ceremonial chamber with stained-glass windows and wood-paneled walls.

The advocates had contributed to the defeat of same-sex marriage in 2009, he told them, with their rampant infighting and disorganization. He had seen it firsthand, as attorney general, when organizers had given him wildly divergent advice about which senators to lobby and when, sometimes in bewildering back-to-back telephone calls. ?You can either focus on the goal, or we can spend a lot of time competing and destroying ourselves,? the governor said.

This time around, the lobbying had to be done the Cuomo way: with meticulous, top-down coordination. ?I will be personally involved,? he said.

The gay-rights advocates agreed, or at least acquiesced. Five groups pushing for same-sex marriage merged into a single coalition, hired a prominent consultant with ties to Mr. Cuomo?s office, Jennifer Cunningham, and gave themselves a new name: New Yorkers United for Marriage.

Those who veered from the script faced swift reprimand. When Assemblyman Daniel J. O?Donnell, an openly gay Democrat from Manhattan, introduced a same-sex marriage bill in May without first alerting the governor?s office, he was upbraided by Mr. Cohen. ?What do you think you?re doing?? the governor?s aide barked over the phone.

Danny Hakim contributed reporting.

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Blog - Talk 'n' talc